Detecting "occult" viral infection after marrow transplantation
نویسندگان
چکیده
منابع مشابه
Detecting "occult" viral infection after marrow transplantation.
In this issue of the Journal, BARBERÁ et al. [1] report on the detection of previously unsuspected Cytomegalovirus (CMV) pulmonary infection in the lungs of marrow transplant recipients who died with evidence of diffuse alveolar damage [1]. Detection of such "occult" infections is of great importance and would have major implications for the care of marrow recipients. Viral pneumonia has been t...
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Cytomegalovirus (CMV) infection was detected in 65 of 143 (45%) autologous bone marrow transplant (BMT) patients. CMV pneumonitis occurred in only 2% of the patients and CMV retinitis occurred in none. Infection occurred in half of the 40 initially seronegative patients and 47% of the 94 initially seropositive patients. Among initially seropositive patients, platelet recovery was slower in infe...
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To the Editor: Antiviral agents including Acyclovir have been ineffective for this complication because they affect only the replicative phase of EBV Epstein-Barr virus (EBV) lymphoproliferation is now a signifiinfection and cannot modify the growth oftransformed B cells. Oetcant cause of morbidity and mortality after mismatched family or tle et a l l recently reported a patient who develo...
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Representatives of 17 bone marrow transplant (BMT) teams met to discuss the problems of infection after BMT. With experience of more than 2200 transplanted patients over the past 10 yr, the changes in the patterns of infection were surprisingly similar. Deaths due purely to bacterial infection have greatly diminished and the major early problems today result from fungi and cytomegalovirus. The ...
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We prospectively documented the development of a fatal, secondarily acquired severe immunodeficiency in a 19-year-old man who underwent uncomplicated bone marrow transplantation. He had no graft v host disease (GVHD) and had normal recovery of his immune system as determined by lymphocyte phenotyping, mitogenic responses of his peripheral blood lymphocytes, and his ability to secrete immunoglob...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 1996
ISSN: 0000-0000,0903-1936
DOI: 10.1183/09031936.96.09061115